Guide to the practical teaching
of biology and genetics

Non-Mendelian inheritance

TASK 1:

A man affected with mitochondrial optic neuropathy married a healthy woman. What is the probability that their child will be affected with this disease?

TASK 2:

Recessive mutation in chloroplast DNA causes variegation of leaves in Mirabilis jalapa. What plants can be expected in the offspring of variegated maternal plant and green paternal plant?

TASK 3:

What will be the leaf color of the offspring resulting from pollination of green plant with the pollen of variegated plant?

TASK 4:

What will be genotypes and phenotypes in F₁, F₂ and F₃ generations, when P generation is represented by female snail with left-handed shell and male with right-handed shell.

TASK 5:

What was the genotype and phenotype of parents of an offspring with left-handed shell? What was the phenotype of this offspring?

TASK 6:

The pedigree bellow shows the inheritance of Kearns-Sayre syndrome, a hereditary genetic disease caused by mtDNA mutation. It is myopathy characterized by isolated involvement of the muscles controlling eye-lid and eye movement and by progressive ophthalmoplegia. Mark the affected individuals in the pedigree with black color.